منابع مشابه
Prostate epithelial stem and progenitor cells.
The classic androgen ablation and replacement experiment demonstrates that prostate epithelia possess extensive regenerative capacities and implies the existence of the prostate stem/progenitor cells. These cells may serve as the cells of origin for prostate cancer and their intrinsic property may dictate the clinical behaviors of the resulting diseases. Therefore, detailed characterization of ...
متن کاملUlcert Repair by Spray of Epithelial Stem Cells
Purpose: Separation, prolifration of stem cells and repairing of injured parts using these cells. Materials and Methods: This was a Lab-Experimental study. We used 6 male albino rabbits. At first, under general anesthesia 5x5 cm2 full thickness skin from one of the rabbits separated, washed using 70% alcohol and inserted in cold HBSS. Then it was cut into 4-6 mm pieces, washed again and incubat...
متن کاملProximal location of mouse prostate epithelial stem cells
Stem cells are believed to regulate normal prostatic homeostasis and to play a role in the etiology of prostate cancer and benign prostatic hyperplasia. We show here that the proximal region of mouse prostatic ducts is enriched in a subpopulation of epithelial cells that exhibit three important attributes of epithelial stem cells: they are slow cycling, possess a high in vitro proliferative pot...
متن کاملNDRG2 Regulates the Expression of Genes Involved in Epithelial Mesenchymal Transition of Prostate Cancer Cells
Background: Metastasis is the main cause of prostate cancer (PCa) death. The inhibitory effect of N-myc downstream-regulated gene 2 (NDRG2) on the invasiveness properties of PCa cells has been demonstrated previously. However, its underlying mechanisms have not yet been investigated. The present study aimed to investigate the effects of NDRG2 overexpression on the expression of genes involved i...
متن کاملProstate stem cell antigen is a marker of late intermediate prostate epithelial cells.
Prostate stem cell antigen (PSCA, named for its strong sequence homology to the thymocyte marker stem cell antigen 2) is a cell surface antigen expressed in normal prostate and associated with human and murine prostate cancer. To begin to investigate a possible link between PSCA expression in normal prostate and prostate carcinogenesis, we characterized the phenotype and proliferative behavior ...
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ژورنال
عنوان ژورنال: Cell Proliferation
سال: 2005
ISSN: 0960-7722,1365-2184
DOI: 10.1111/j.1365-2184.2005.00356.x